Theories of Aging: An Ever-Evolving Field

Cover Page

Cite item

Full Text

Abstract

Senescence has been the focus of research for many centuries. Despite significant progress in extending average human life expectancy, the process of aging remains largely elusive and, unfortunately, inevitable. In this review, we attempted to summarize the current theories of aging and the approaches to understanding it.

About the authors

P. V. Sergiev

Belozersky Institute of Physico-Chemical Biology; Moscow State University

Author for correspondence.
Email: petya@genebee.msu.ru
Россия

O. A. Dontsova

Belozersky Institute of Physico-Chemical Biology; Moscow State University

Email: petya@genebee.msu.ru
Россия

G. V. Berezkin

ESN group

Email: petya@genebee.msu.ru
Россия

References

  1. Giorgio M., Migliaccio E., Orsini F., Paolucci D., Moroni M., Contursi C., Pelliccia G., Luzi L., Minucci S., Marcaccio M. // Cell. 2005, V.122, P.221-233
  2. Skulachev V.P. // IUBMB Life. 2000, V.49, P.177-180
  3. Dufour E., Boulay J., Rincheval V., Sainsard-Chanet A. // Proc. Natl. Acad. Sci. USA. 2000, V.97, P.4138-4143
  4. Harman D. // J. Gerontol. 1956, V.11, P.298-300
  5. Skulachev V.P. // Biochemistry (Mosc). 2007, V.72, P.1385-1396
  6. Harman D. // J. Am. Geriatr. Soc. 1972, V.20, P.145-147
  7. de Grey A.D. // Bioessays. 1997, V.19, P.161-166
  8. Barja G. // Free Radic. Biol. Med. 2002, V.33, P.1167-1172
  9. Andziak B., O’Connor T.P., Qi W., DeWaal E.M., Pierce A., Chaudhuri A.R., van Remmen H., Buffenstein R. // Ageing Cell. 2006, V.5, P.463-471
  10. Labunskyy V.M., Gladyshev V.N. // Antioxid. Redox Signal. 2013, V.19, P.1362-1372
  11. Schriner S.E., Linford N.J., Martin G.M., Treuting P., Ogburn C.E., Emond M., Coskun P.E., Ladiges W., Wolf N., van Remmen H. // Science. 2005, V.308, P.1909-1911
  12. Sun J., Tower J. // Mol. Cell Biol. 1999, V.19, P.216-228
  13. van Raamsdonk J.M., Hekimi S. // PLoS Genet. 2009, V.5, P.e1000361
  14. Gladyshev V.N. // Bioessays. 2012, V.34, P.925-929
  15. Gladyshev V.N. // Trends Genet. 2013, V.29, P.506-512
  16. Brunk U.T., Terman A. // Eur. J. Biochem. 2002, V.269, P.1996-2002
  17. Schachter F., Faure-Delanef L., Guenot F., Rouger H., Froguel P., Lesueur-Ginot L., Cohen D. // Nat. Genet. 1994, V.6, P.29-32
  18. Huang Y., Mucke L. // Cell. 2012, V.148, P.1204-1222
  19. Russo C., Violani E., Salis S., Venezia V., Dolcini V., Damonte G., Benatti U., D’Arrigo C., Patrone E., Carlo P. // J. Neurochem. 2002, V.82, P.1480-1489
  20. Sell D.R., Monnier V.M. // Gerontology. 2012, V.58, P.227-237
  21. Monnier V.M., Sell D.R. // Rejuvenation Res. 2006, V.9, P.264-273
  22. Franceschi C., Bonafe M., Valensin S. // Vaccine. 2000, V.18, P.1717-1720
  23. Dilman V.M. // Lancet. 1971, V.1, P.1211-1219
  24. Dilman V.M., Anisimov V.N. // Exp. Gerontol. 1979, V.14, P.161-174
  25. Olovnikov A.M. // Dokl Akad Nauk SSSR. 1971, V.201, P.1496-1499
  26. Greider C.W., Blackburn E.H. // Cell. 1985, V.43, P.405-413
  27. Harley C.B., Futcher A.B., Greider C.W. // Nature 1990, V.345, P.458-460
  28. Hayflick L., Moorhead P.S. // Exp. Cell Res. 1961, V.25, P.585-621
  29. Kim N.W., Piatyszek M.A., Prowse K.R., Harley C.B., West M.D., Ho P.L., Coviello G.M., Wright W.E., Weinrich S.L., Shay J.W. // Science. 1994, V.266, P.2011-2015
  30. McCay C.M., Crowell M.F., Maynard L.A. // Discussion 172 // Nutrition. 1989, V.5, P.155-171
  31. Kenyon C., Chang J., Gensch E., Rudner A., Tabtiang R. // Nature 1993, V.366, P.461-464
  32. Anisimov V.N. // Molecular and Physiological Mechanisms of Aging. St.Petersburg.: Nauka, 2008 2008, P.481
  33. Finch C.E., Ruvkun G. // Annu. Rev. Genomics Hum. Genet. 2001, V.2, P.435-462
  34. Tissenbaum H.A., Guarente L. // Nature 2001, V.410, P.227-230
  35. Weismann A. // Ueber die Dauer des Lebens, ein Vortrag. Jena: G. Fischer, 1882. 1982, P.94
  36. Skulachev V.P. . // Biochemistry (Mosc). 2012, P.77-846
  37. Boiko A.G. // Zh Obshch Biol. 2007, V.68, P.35-51
  38. Ziuganov V.V. // Izv Akad Nauk Ser Biol. 2005, V.4, P.435-441
  39. Popov I.Yu. // Adv. gerontol. 2009, V.22, P.596-604
  40. Fisher D.O., Double M.C., Blomberg S.P., Jennions M.D., Cockburn A. // Nature 2006, V.444, P.89-92
  41. Kirkwood T.B.L. // Nature 1977, V.270, P.301-304
  42. Brooks-Wilson A.R. // Hum. Genet. 2013, V.132, P.1323-1338
  43. Deelen J., Uh H.W., Monajemi R., van Heemst D., Thijssen P.E., Bohringer S., van den Akker E.B., de Craen A.J., Rivadeneira F., Uitterlinden A.G. // Age (Dordr.). 2013, V.35, P.235-249
  44. Newman A.B., Murabito J.M. // Epidemiol. Rev. 2013, V.35, P.181-197
  45. Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A. // Science. 2001, V.291, P.1304-1351
  46. Austad S.N. // Mech. Ageing Dev. 2005, V.126, P.43-49
  47. Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L., Marino S.M., Sun X., Turanov A.A., Yang P. // Nature 2011, V.479, P.223-227
  48. Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y., Turanov A.A., Zhu Y., Lenz T.L. // Nat. Commun. 2013, V.4, P.2212
  49. Ebert T.A. // Exp. Gerontol. 2008, V.43, P.734-738
  50. Ebert T.A., Southon J.R. // Fish. Bull. 2003, V.101, P.915-922
  51. Francis N., Gregg T., Owen R., Ebert T., Bodnar A. // FEBS Lett. 2006, V.580, P.4713-4717

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2015 Sergiev P.V., Dontsova O.A., Berezkin G.V.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies