The Evolutionary Pathway of X Chromosome Inactivation in Mammals
- Authors: Shevchenko A.I.1,2,3, Zakharova I.S.1,2,3, Zakian S.M.1,2,3
-
Affiliations:
- Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences
- State Research Institute of Circulation Pathology
- Institute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences
- Issue: Vol 5, No 2 (2013)
- Pages: 40-53
- Section: Reviews
- Submitted: 17.01.2020
- Published: 15.06.2013
- URL: https://actanaturae.ru/2075-8251/article/view/10596
- DOI: https://doi.org/10.32607/20758251-2013-5-2-40-53
- ID: 10596
Cite item
Abstract
X chromosome inactivation is a complex process that occurs in marsupial and eutherian mammals. The process is thought to have arisen during the differentiation of mammalian sex chromosomes to achieve an equal dosage of X chromosome genes in males and females. The differences in the X chromosome inactivation processes in marsupial and eutherian mammals are considered, and the hypotheses on its origin and evolution are discussed in this review.
Keywords
About the authors
A. I. Shevchenko
Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences; State Research Institute of Circulation Pathology; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences
Email: zakian@bionet.nsc.ru
Россия
I. S. Zakharova
Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences; State Research Institute of Circulation Pathology; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences
Email: zakian@bionet.nsc.ru
Россия
S. M. Zakian
Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences; State Research Institute of Circulation Pathology; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences
Author for correspondence.
Email: zakian@bionet.nsc.ru
Россия
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