Pulsed Electron Double Resonance in Structural Studies of Spin-Labeled Nucleic Acids

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Abstract

This review deals with the application of the pulsed electron double resonance (PELDOR) method to studies of spin-labeled DNA and RNA with complicated spatial structures, such as tetramers, aptamers, riboswitches, and three- and four-way junctions. The use of this method for studying DNA damage sites is also described.

About the authors

O. S. Fedorova

Institute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences

Author for correspondence.
Email: fedorova@niboch.nsc.ru
Russian Federation

Yu. D. Tsvetkov

Institute of Chemical Kinetics and Combustion, Siberian Branch, Russian Academy of Sciences

Email: fedorova@niboch.nsc.ru
Russian Federation

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