Email this article Detection of T-Cadherin Expression in Mouse Embryos
- Authors: Rubina К.А.1, Smutova V.А.1, Semenova М.L.1, Poliakov А.А.2, Gerety S.3, Wilkinson D.2, Surkova Е.I.1, Semina Е.V.1, Sysoeva V.Y.1, Tkachuk V.А.1
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Affiliations:
- Lomonosov Moscow State University
- MRC National Institute for Medical Research
- Wellcome Trust Sanger Institute
- Issue: Vol 7, No 2 (2015)
- Pages: 87-94
- Section: Research Articles
- Submitted: 17.01.2020
- Published: 15.06.2015
- URL: https://actanaturae.ru/2075-8251/article/view/10506
- DOI: https://doi.org/10.32607/20758251-2015-7-2-87-94
- ID: 10506
Cite item
Abstract
The aim of the present study was to evaluate T-cadherin expression at the early developmental stages of the mouse embryo. Using in situ hybridization and immunofluorescent staining of whole embryos in combination with confocal microscopy, we found that T-cadherin expression is detected in the developing brain, starting with the E8.75 stage, and in the heart, starting with the E11.5 stage. These data suggest a possible involvement of T-cadherin in the formation of blood vessels during embryogenesis.
Keywords
About the authors
К. А. Rubina
Lomonosov Moscow State University
Author for correspondence.
Email: rkseniya@mail.ru
Russian Federation
V. А. Smutova
Lomonosov Moscow State University
Email: rkseniya@mail.ru
Russian Federation
М. L. Semenova
Lomonosov Moscow State University
Email: rkseniya@mail.ru
Russian Federation
А. А. Poliakov
MRC National Institute for Medical Research
Email: rkseniya@mail.ru
United Kingdom
S. Gerety
Wellcome Trust Sanger Institute
Email: rkseniya@mail.ru
United Kingdom
D. Wilkinson
MRC National Institute for Medical Research
Email: rkseniya@mail.ru
United Kingdom
Е. I. Surkova
Lomonosov Moscow State University
Email: rkseniya@mail.ru
Russian Federation
Е. V. Semina
Lomonosov Moscow State University
Email: rkseniya@mail.ru
Russian Federation
V. Yu Sysoeva
Lomonosov Moscow State University
Email: rkseniya@mail.ru
Russian Federation
V. А. Tkachuk
Lomonosov Moscow State University
Email: rkseniya@mail.ru
Russian Federation
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