Detection of T-Cadherin Expression in Mouse Embryos
Authors:
Rubina К.А. 1 , Smutova V.А. 1 , Semenova М.L. 1 , Poliakov А.А. 2 , Gerety S. 3 , Wilkinson D. 2 , Surkova Е.I. 1 , Semina Е.V. 1 , Sysoeva V.Y. 1 , Tkachuk V.А. 1
Affiliations:
Lomonosov Moscow State University
MRC National Institute for Medical Research
Wellcome Trust Sanger Institute
Issue: Vol 7, No 2 (2015)Pages: 87-94Section:
Research Articles
Submitted: 17.01.2020Published: 15.06.2015URL: https://actanaturae.ru/2075-8251/article/view/10506 DOI: https://doi.org/10.32607/20758251-2015-7-2-87-94 ID: 10506
Cite item
Abstract
The aim of the present study was to evaluate T-cadherin expression at the early developmental stages of the mouse embryo. Using in situ hybridization and immunofluorescent staining of whole embryos in combination with confocal microscopy, we found that T-cadherin expression is detected in the developing brain, starting with the E8.75 stage, and in the heart, starting with the E11.5 stage. These data suggest a possible involvement of T-cadherin in the formation of blood vessels during embryogenesis.
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Copyright (c) 2015 Rubina К.А., Smutova V.А., Semenova М.L., Poliakov А.А., Gerety S., Wilkinson D., Surkova Е.I., Semina Е.V., Sysoeva V.Y., Tkachuk V.А.
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