Detection of T-Cadherin Expression in Mouse Embryos

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Abstract


The aim of the present study was to evaluate T-cadherin expression at the early developmental stages of the mouse embryo. Using in situ hybridization and immunofluorescent staining of whole embryos in combination with confocal microscopy, we found that T-cadherin expression is detected in the developing brain, starting with the E8.75 stage, and in the heart, starting with the E11.5 stage. These data suggest a possible involvement of T-cadherin in the formation of blood vessels during embryogenesis.


К. А. Rubina

Lomonosov Moscow State University

Author for correspondence.
Email: rkseniya@mail.ru

Russian Federation

V. А. Smutova

Lomonosov Moscow State University

Email: rkseniya@mail.ru

Russian Federation

М. L. Semenova

Lomonosov Moscow State University

Email: rkseniya@mail.ru

Russian Federation

А. А. Poliakov

MRC National Institute for Medical Research

Email: rkseniya@mail.ru

United Kingdom

S. Gerety

Wellcome Trust Sanger Institute

Email: rkseniya@mail.ru

United Kingdom

D. Wilkinson

MRC National Institute for Medical Research

Email: rkseniya@mail.ru

United Kingdom

Е. I. Surkova

Lomonosov Moscow State University

Email: rkseniya@mail.ru

Russian Federation

Е. V. Semina

Lomonosov Moscow State University

Email: rkseniya@mail.ru

Russian Federation

V. Yu Sysoeva

Lomonosov Moscow State University

Email: rkseniya@mail.ru

Russian Federation

V. А. Tkachuk

Lomonosov Moscow State University

Email: rkseniya@mail.ru

Russian Federation

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Copyright (c) 2015 Rubina К.А., Smutova V.А., Semenova М.L., Poliakov А.А., Gerety S., Wilkinson D., Surkova Е.I., Semina Е.V., Sysoeva V.Y., Tkachuk V.А.

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