Title | Fig. 4. Insertion of the Myb transcription factor binding site activates the super-enhancer-driven expression of the TAL1 oncogene. The DNA-bound Myb recruits the cyclic AMP response element binding protein (CBP) and its partner, histone acetylase H3K2, to activate chromatin in the super-enhancer region. Additional transcription factors are also recruited |
Submission | Super-Enhancers in the Regulation of Gene Transcription: General Aspects and Antitumor Targets |
Type | — |
Date | 2021-04-19 |
Digital Object Identifier | https://doi.org/10.32607/20758251-2021-13-1-4-15-2144 |
Supplementary File
File Name | 11067-4374-1-SP.jpg |
Original file name | Bruter_4.jpg |
File Size | 293KB |
Date uploaded | 19.04.2021 23:00 |