Title |
Fig. 1. Effects of amitriptyline (10 mg/kg) and fluoxetine (20 mg/kg) under UCMS in the forced swim test in mice. A – duration of immobility period; B – duration of swimming; C – duration of climbing. The data are presented as M ± SEM; Without stress and control – 0.9% NaCl (0.1 ml/10 g body weight); UMCS – unpredictable chronic mild stress; FLX – fluoxetine, AMT – amitriptyline; acute – single administration; chr. – chronic administration during 28 days. ### – p < 0.001 compared with the non-stressed group; * – p < 0.05; ** p < 0.01; *** – p < 0.001 compared with the saline group under stress; xxx – p <0.001; xx – р < 0.01 compared with single administration |