Acta NaturaeActa NaturaeActa Naturae2075-8251Acta Naturae Ltd1075910.32607/20758251-2010-2-3-47-61ArticlesСтатьиReview ArticleProtein Engineering of Penicillin AcylaseProtein Engineering of Penicillin AcylaseTishkovV Ivitishkov@gmail.comSavinS SYasnayaA SLomonosov Moscow State UniversityBach Institute of Biochemistry, Russian Academy of SciencesInnovations and High Technologies MSU LtdBach Institute of Biochemistry, Russian Academy of SciencesInnovations and High Technologies MSU LtdNational Research Center "Kurchatovskii Institute"1509201023VOL 2, NO3 (2010)ТОМ 2, №3 (2010)476117012020Copyright ©; 2010, Tishkov V.I., Savin S.S., Yasnaya A.S.Copyright ©; 2010, Tishkov V.I., Savin S.S., Yasnaya A.S.2010Tishkov V.I., Savin S.S., Yasnaya A.S.Tishkov V.I., Savin S.S., Yasnaya A.S.https://creativecommons.org/licenses/by/4.0https://actanaturae.ru/2075-8251/article/view/10759

Penicillin acylases (PA) are widely used for the production of semi-synthetic β-lactam antibiotics and chiral compounds. In this review, the latest achievements in the production of recombinant enzymes are discussed, as well as the results of PA type G protein engineering.

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