Acta NaturaeActa NaturaeActa Naturae2075-8251Acta Naturae Ltd1067410.32607/20758251-2011-3-2-22-33ArticlesСтатьиResearch ArticlePosttranslational Modifications of Ribosomal Proteins in Escherichia coliPosttranslational Modifications of Ribosomal Proteins in Escherichia coliNesterchukM Vnesterchuk.mihail@gmail.comSergievP VDontsovaO ABelozersky Institute of Physico-Chemical BiologyLomonosov Moscow State UniversityLomonosov Moscow State UniversityBelozersky Institute of Physico-Chemical Biology1506201132VOL 3, NO2 (2011)ТОМ 3, №2 (2011)223317012020Copyright ©; 2011, Nesterchuk M.V., Sergiev P.V., Dontsova O.A.Copyright ©; 2011, Nesterchuk M.V., Sergiev P.V., Dontsova O.A.2011Nesterchuk M.V., Sergiev P.V., Dontsova O.A.Nesterchuk M.V., Sergiev P.V., Dontsova O.A.https://creativecommons.org/licenses/by/4.0https://actanaturae.ru/2075-8251/article/view/10674

A number of ribosomal proteins in Escherichia coli undergo posttranslational modifications. Six ribosomal proteins are methylated (S11, L3, L11, L7/L12, L16, and L33), three proteins are acetylated (S5, S18, and L7), and protein S12 is methylthiolated. Extra amino acid residues are added to protein S6. C-terminal amino acid residues are partially removed from protein L31. The functional significance of these modifications has remained unclear. These modifications are not vital to the cells, and it is likely that they have regulatory functions. This paper reviews all the known posttranslational modifications of ribosomal proteins in Escherichia coli. Certain enzymes responsible for the modifications and mechanisms of enzymatic reactions are also discussed

ribosomal proteinsposttranslational modificationEscherichia coliArnold R.J., Reilly J.P. // Anal. Biochem. 1999. V. 269. P. 105-112.Ben-Bassat A., Bauer K., Chang S.Y., Myambo K., Boosman A., Chang S. // J. Bacteriol. 1987. V. 169. P 751-757.Chang F.N., Budzilowicz C. // J. Bacteriol. 1977. V. 131. P. 105-110.Brosius J. // Biochemistry. 1977. V. 17. P 501-508.Eistetter A.J., Butler PD., Traut R.R., Fanning T.G. // FEMS Microbiol. Lett. 1999. V. 180. P. 345-349.Makarova K.S., Ponomarev V.A., Koonin E.V. // Genome Biol. 2001. V. 2. Research 0033.Gabriel S.E., Helmann J.D. // J. Bacteriol. 2009. V. 191. P. 6116-6122.Polevoda B., Sherman F. // Mol. Microbiol. 2007. V. 65. P. 590-606.Chang C.N., Chang N. // Biochemistry. 1975. V. 14. P 468-477.Dognin M.J., Wittmann-Liebold B. // Eur. J. Biochem. 1980. V. 112. P. 131-151.Chang F.N., Cohen L.B., Navickas I.J., Chang C.N. // Biochemistry. 1975. V. 14. P 4994-4998.Colson C., Lhoest J., Urlings C. // Mol. Gen. Genet. 1979. V. 169. P. 245-250.Demirci H., Gregory S.T., Dahlberg A.E., Jogl G. // EMBO J. 2007. V. 26. P. 567-577.Demirci H., Gregory S.T., Dahlberg A.E., Jogl G. // Structure. 2008. V. 16. P. 1059-1066.Agrawal R.K., Linde J., Sengupta J., Nierhaus K.H., Frank J. // J. Mol. Biol. 2001. V. 311. P. 777-787.Cameron D.M., Thompson J., March PE., Dahlberg A.E. // J. Mol. Biol. 2002. V. 319. P. 27-35.Valle M., Zavialov A., Li W., Stagg S.M., Sengupta J., Nielsen R.C., Nissen P, Harvey S.C., Ehrenberg M., Frank J. // Nat. Struct. Biol. 2003. V. 10. P 899-906.Vanet A., Plumbridge J.A., Guerin M.F., Alix J.H. // Mol. Microbiol. 1994. V. 14. P. 947-958.Colson C., Smith H.O. // Mol. Gen. Genet. 1977. V. 154. P. 167-173.Lhoest J., Colson C. // Mol. Gen. Genet. 1977. V. 154. P. 175-180.Muranova T.A., Muranov A.V., Markova L.F., Ovchinnikov Y.A. // FEBS Lett. 1978. V. 96. P 301-305.Lhoest J., Colson C. // Eur. J. Biochem. 1981. V. 121. P. 33-37.Heurgue-Hamard V., Champ S., Engstrom A., Ehrenberg M., Buckingham R.H. // EMBO J. 2002. V. 21. P 769-778.Kaczanowska M., Ryden-Aulin M. // Microbiol. Mol. Biol. Rev. 2007. V. 71. P. 477-494.Chen R., Chen-Schmeisser U. // Proc. Natl. Acad. Sci. USA. 1977. V. 74. P 4905-4908.David C.L., Keener J., Aswad D.W. // J. Bacteriol. 1999. V. 181. P 2872-2877.Chang F.N. // J. Bacteriol. 1978. V. 135. P. 1165-1166.Gudkov A.T. // FEBS Lett. 1997. V. 407. P 253-256.Brosius J., Chen R. // FEBS Lett. 1976. V. 68. P 105-109.Chang C.N., Schwartz M., Chang F.N. // Biochem. Biophys. Res. Commun. 1976. V. 73. P. 233-239.Polevoda B., Sherman F. // Genome Biol. 2002. V. 3. Review 0006.Vetting M.W., Bareich D.C., Yu M., Blanchard J.S. // Protein. Sci. 2008. V. 17. P. 1781-1790.Miao L., Fang H., Li Y., Chen H. // Biochem. Biophys. Res. Commun. 2007. V. 357. P. 641-647.Wittmann-Liebold B., Greuer B. // FEBS Lett. 1978. V. 95. P. 91-98.Janda I., Kitakawa M., Isono K. // Mol. Gen. Genet. 1985. V. 201. P. 433-436.Yoshikawa A., Isono S., Sheback A., Isono K. // Mol. Gen. Genet. 1987. V. 209. P 481-488.Poot R.A., Jeeninga R.E., Pleij C.W., van Duin J. // FEBS Lett. 1997. V. 401. P 175-179.Cumberlidge A.G., Isono K. // J. Mol. Biol. 1979. V. 131. P 169-189.Roy-Chaudhuri B., Kirthi N., Kelley T., Culver G.M. // Mol. Microbiol. 2008. V. 68. P. 1547-1559.White-Ziegler C.A., Black A.M., Eliades S.H., Young S., Porter K. // J. Bacteriol. 2002. V. 184. P. 4334-4342.Yaguchi M. // FEBS Lett. 1975. V. 59. P. 217-220.Isono K., Isono S. // Mol. Gen. Genet. 1980. V. 177. P. 645-651.Recht M.I., Williamson J.R. // J. Mol. Biol. 2001. V. 313. P. 35-48.Terhorst C., Moller W., Laursen R., Wittmann-Liebold B. // Eur. J. Biochem. 1973. V. 34. P. 138-152.Tanaka S., Matsushita Y., Yoshikawa A., Isono K. // Mol. Gen. Genet. 1989. V. 217. P. 289-293.Isono S., Isono K. // Mol. Gen. Genet. 1981. V. 183. P. 473-477.Ramagopal S., Subramanian A.R. // Proc. Natl. Acad. Sci. USA. 1974. V. 71. P. 2136-2140.Gordiyenko Y., Deroo S., Zhou M., Videler H., Robinson C.V. // J. Mol. Biol. 2008. V. 380. P 404-414.Vetting M.W., de Carvalho L.P., Roderick S.L., Blanchard J.S. // J. Biol. Chem. 2005. V. 280. P. 22108-22114.Funatsu G., Yaguchi M., Wittmann-Liebold B. // FEBS Lett. 1977. V. 73. P. 12-17.Post L.E., Nomura M. // J. Biol. Chem. 1980. V. 255. P. 4660-4666.Kowalak J.A., Walsh K.A. // Protein. Sci. 1996. V. 5. P. 1625-1632.Anton B.P., Saleh L., Benner J.S., Raleigh E.A., Kasif S., Roberts R.J. // Proc. Natl. Acad. Sci. USA. 2008. V. 105. P. 1826-1831.Booker S.J., Cicchillo R.M., Grove T.L. // Curr. Opin. Chem. Biol. 2007. V. 11. P. 543-552.Fontecave M., Mulliez E., Atta M. // Chem. Biol. 2008. V. 15. P. 209-210.Lee K.H., Saleh L., Anton B.P., Madinger C.L., Benner J.S., Iwig D.F., Roberts R.J., Krebs C., Booker S.J. // Biochemistry. 2009. V. 48. P 10162-10174.Strader M.B., Costantino N., Elkins C.A., Chen C.Y., Patel I., Makusky A.J., Choy J.S., Court D.L., Markey S.P, Kowalak J.A. // Mol. Cell. Proteomics. 2011. V. 10. M110.005199.Arragain S., Garcia-Serres R., Blondin G., Douki T., Clemancey M., Latour J.M., Forouhar F., Neely H., Montelione G.T., Hunt J.F., et al.// J. Biol. Chem. 2010. V. 285. N 8. P 5792-5801.Asatryan L.S., Spirin A.S. // Mol. Gen. Genet. 1975. V. 138. P 315-321.Hitz H., Schafer D., Wittmann-Liebold B. // FEBS Lett. 1975. V. 56. P 259-262.Hitz H., Schafer D., Wittmann-Liebold B. // Eur. J. Biochem. 1977. V. 75. P 497-512.Schnier J., Kitakawa M., Isono K. // Mol. Gen. Genet. 1986. V. 204. P 126-132.Reeh S., Pedersen S. // Mol. Gen. Genet. 1979. V. 173. P 183-187.Kang W.K., Icho T., Isono S., Kitakawa M., Isono K. // Mol. Gen. Genet. 1989. V. 217. P. 281-288.Kade B., Dabbs E.R., Wittmann-Liebold B. // FEBS Lett. 1980. V. 121. P 313-316.Kitakawa M., Blumenthal L., Isono K. // Mol. Gen. Genet. 1980. V. 180. P 343-349.