Acta NaturaeActa NaturaeActa Naturae2075-8251Acta Naturae Ltd1065310.32607/20758251-2011-3-4-30-37ArticlesСтатьиReview ArticleMesenchymal Stem Cells in Tissue Growth and RepairMesenchymal Stem Cells in Tissue Growth and RepairKalininaN I

Department of Fundamental Medicine

n_i_kalinina@mail.ruSysoevaV Yu

Department of Fundamental Medicine

RubinaK A

Department of Fundamental Medicine

ParfenovaYe V

Department of Fundamental Medicine

TkachukV A

Department of Fundamental Medicine

Lomonosov Moscow State University1512201134VOL 3, NO4 (2011)ТОМ 3, №4 (2011)303717012020Copyright ©; 2011, Kalinina N.I., Sysoeva V.Y., Rubina K.A., Parfenova Y.V., Tkachuk V.A.Copyright ©; 2011, Kalinina N.I., Sysoeva V.Y., Rubina K.A., Parfenova Y.V., Tkachuk V.A.2011Kalinina N.I., Sysoeva V.Y., Rubina K.A., Parfenova Y.V., Tkachuk V.A.Kalinina N.I., Sysoeva V.Y., Rubina K.A., Parfenova Y.V., Tkachuk V.A.https://creativecommons.org/licenses/by/4.0https://actanaturae.ru/2075-8251/article/view/10653

It has been established in the recent several decades that stem cells play a crucial role in tissue renewal and regeneration. Mesenchymal stem cells (MSCs) are part of the most important population of adult stem cells.bentley replica kits These cells have hereby been identified for the very first time and subsequently isolated from bone marrow stroma. Bone marrow-derived MSCs have been believed to play the role of a source of cells for the renewal and repair of connective tissues, including bone, cartilage and adipose tissues. Cells similar to bone marrow-derived MSCs have now been identified in all postnatal tissues. Data on rolex replica watch the distribution and function of MSCs in vivo collected using novel approaches pertaining to the identification of MSCs in situ, to their isolation from tissues, and finally to the determination of their biological properties have enabled successful revision of the role of MSCs in various organs and tissues. This review summarizes our own, as well as others’, data concerning the role of MSCs in the regulation processes of tissue repair and regeneration. In our opinion, MSCs provide the connection between the blood-vascular, immune, endocrine, repair rolex replica and nervous systems and tissue-specific stem cells in the body.

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